SIROCCO
SIROCCO research consortium includes over 30 partners and aims to explore the full complement of miRNAs and siRNAs in animals and plants. Using bioinformatics, genomics, biochemistry, cell biology and genetics, the consortium members study how these RNAs are produced and processed, how they are transported and how they target specific genes and RNAs for silencing.
The outputs of SIROCCO will include databases of silencing RNA sequence and function in several organisms, new technologies for detection and manipulation of these RNAs, and information that will allow siRNA and miRNA profiles to be used as molecular markers and diagnostic methods for natural biological variation including the perturbations associated with disease.
AIMS
SUMMIT
SUMMIT (Surrogate markers for vascular Micro- and Macrovascular hard endpoints for Innovative diabetes Tools) is part of the joint undertaking by the EU and the pharmaceutical industry under the name IMI (Innovative Medicines Initiative). The 40 million dollar collaboration of 18 research groups is coordinated by Boehringer Ingelheim International GmbH and the Diabetes Center at Lund University (LUDC).
Services for harmonization of summary phenotypic information across multiple cohorts contributing to SUMMIT to support estimation of sample numbers for specific case-control comparisons, and identification of the most valuable individuals for the SUMMIT-funded GWAS studies.
sail.simbioms.org/SUMMIT (secure access, consortium members only)
BBMRI.fi
MBC (Meilahti Campus Biobank) is joint effort between FIMM and its partner organizations National Institute for Health and Welfare (THL), Hospital District of Helsinki and Uusimaa (HUS) and University of Helsinki (HY).
Availability database is part of the Web portal of the MCB. Purpose of the portal is to give information on sample and data resources available on the biobank and provide easy to use query interface for resource discovery. The portal is based on the SAIL application (weblink available soon).
BBMRI.no
HUNT Biosciences offers access to HUNT Databank, a fully established Norwegian population-based prospective biobank, leveraging more than 25 years of medical records and biological samples, representing a regional cohort of close to 100.000 individuals. In addition to genetic samples, HUNT Databank comprise more than 800 exposure variables and nearly 3000 different variables per individual. HUNT Databank is part of the Faculty of Medicine, Norwegian University of Science and Technology (NTNU) in Trondheim and a part of Norwegian branch (BBMRI.no) of international strategic initiative - Biobanking and Biomolecular Resources Research Infrastructure.
Collaboration between HUNT Biosciences and SIMBioMS (as a part of the HUNT Scientific Inventory project) resulted in harmonisation of three collections of HUNT databank with the ENGAGE cohorts (10 sample collections). The availability information concerning metabolic syndrome data (sail.simbioms.org) is one of multiple case studies carried out by SIMBioMS as a part of BBMRI and ELIXIR initiatives.
ENGAGE
ENGAGE (European Network for Genetic and Genomic Epidemiology) is a research project funded with 12 million Euros by the European Commission under the 7th Framework Programme-Health Theme.
The project duration is five years, starting from January 1st, 2008.
Services for data harmonisation, phenotype mapping and sample availability portal for the ENGAGE cohorts as well as for the EUTwin and other sample collections outside ENGAGE.
Members area
AIMS
SIMS
SAIL
MolPAGE
MolPAGE, EU P6 integrated project, brought together a consortium of 19 leading academic institutions, biotechnology and pharmaceutical companies. The consortium aimed to tackle diabetes and one of its major complications, vascular disease, through the development and application of a range of genomic, proteomic and metabonomic technology platforms to carry out ‘molecular phenotyping’ on a medium to epidemiological scale.
See partners
AIMS
SIMS
FFM
Stem-cell therapy for CVD patients (Russian federation)
A database of post-myocardial infarction patients treated in 6 hospitals in Russia using stem cells. Department of Fundamental Medicine, Moscow State university.
sail.simbioms.org/ffm
MUTHER
The MuTHER project is undertaking a coordinated program of analysis designed to understand the relationships between genome sequence variation, methylation status, mRNA expression and disease phenotypes. The project aims to develop a resource of detailed genetic (SNP-genotyping; re-sequencing) and genomic (expression; methylation) data from a range of tissues (adipose, skin, skeletal muscle, lymphocytes and lymphoblastoid cell lines) collected from a set of ~900 well-phenotyped UK twins, as to support efforts to understand mechanisms involved in common trait susceptibility.
EGG
The EGG (Early Growth Genetics) consortium is an international collaboration network for the study of fetal and childhood growth genetics.
EGG Data Submission Guide
EGG Data Analyzer Guide
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Services
